"ଏଟିପିକାଲ୍ ଆଣ୍ଟିସାଇକୋଟିକ" ପୃଷ୍ଠାର ସଂସ୍କରଣ‌ଗୁଡ଼ିକ ମଧ୍ୟରେ ତଫାତ

<!-- Clinical data -->|Use=[[psychomotor agitation|Agitation]], [[schizophrenia]],[[bipolar disorder|bipolar]]<ref name=Hitch2019>{{Cite book|last=Hitchings|first=Andrew|url=https://books.google.com/books?id=FPx0DwAAQBAJ|title=The Top 100 Drugs: Clinical Pharmacology and Practical Prescribing|last2=Lonsdale|first2=Dagan|last3=Burrage|first3=Daniel|last4=Baker|first4=Emma|date=2019|publisher=Elsevier|isbn=978-0-7020-7442-4|edition=2nd|pages=80|language=en}}</ref>|Mode_of_action=|Mechanism_of_action=|Biological_target=[[Dopamine receptor]] and [[5-HT receptors|serotonin receptor]]<ref name=Stat2021>{{cite journal |last1=Willner |first1=K |last2=Vasan |first2=S |last3=Abdijadid |first3=S |title=Atypical Antipsychotic Agents |date=January 2021 |pmid=28846323}}</ref>|Chemical_class=<!-- External links -->|Drugs.com={{Drugs.com|drug-class|atypical-antipsychotics}}|medicinenet=|rxlist=}}'''ଆଟିପିକାଲ୍ ଆଣ୍ଟିସାଇକୋଟିକ''' ([[ଇଂରାଜୀ ଭାଷା|ଇଂରାଜୀ ଭାଷାରେ]] '''Atypical antipsychotics/''' '''AAP''' ) ହେଉଛି [[ଆଣ୍ଟିସାଇକୋଟିକ|ଆଣ୍ଟିସାଇକୋଟିକ୍]] ଶ୍ରେଣୀର ଏକ ପ୍ରକାର ଔଷଧ | <ref name="Stat2021autogen2">{{Cite journal|last=Willner|first=K|last2=Vasan|first2=S|last3=Abdijadid|first3=S|date=January 2021|title=Atypical Antipsychotic Agents|pmid=28846323}}</ref> ମୁଖ୍ୟତଃ ଉତ୍ତେଜନା, [[ସିଜୋଫ୍ରେନିଆ]] ଏବଂ [[ବାଇପୋଲାର ଡିଜଅଡର]] ରୋଗମାନଙ୍କ ପାଇଁ ଏହା ବ୍ୟବହୃତ ହୁଏ | <ref name="Hitch2019autogen3">{{Cite book|url=https://books.google.com/books?id=FPx0DwAAQBAJ|title=The Top 100 Drugs: Clinical Pharmacology and Practical Prescribing|last=Hitchings|first=Andrew|last2=Lonsdale|first2=Dagan|last3=Burrage|first3=Daniel|last4=Baker|first4=Emma|date=2019|publisher=Elsevier|isbn=978-0-7020-7442-4|edition=2nd|pages=80|language=en}}</ref> ଅନ୍ୟାନ୍ୟ ବ୍ୟବହାରରେ [[ଅଟିଜିମ୍‌|ଅଟିଜିମ୍]] କିମ୍ବା [[ଅବସାଦ]] ନିମନ୍ତେ ମଧ୍ୟ ବ୍ୟବ‌ହାର ହୋଇଥାଏ | <ref name="Drugs2021">{{Cite web|url=https://www.drugs.com/drug-class/atypical-antipsychotics.html|title=List of Atypical Antipsychotics + Uses, Types & Side Effects|website=Drugs.com|language=en|access-date=22 April 2021}}</ref> ଏହି ଶ୍ରେଣୀର ବିଭନ୍ନ ଔଷଧମାନଙ୍କ ମଧ୍ୟରେ ଗୋଟିଏ ଅନ୍ୟଠାରୁ ଅଧିକ ପ୍ରଭାବଶାଳୀ ଭାବରେ କୌଣସି ସ୍ପଷ୍ଟ ପ୍ରମାଣ ନାହିଁ | <ref name="Stat2021">{{cite journal |last1=Willner |first1=K |last2=Vasan |first2=S |last3=Abdijadid |first3=S |title=Atypical Antipsychotic Agents |date=January 2021 |pmid=28846323}}</ref> <ref name="Drugs2021autogen1">{{cite web |title=List of Atypical Antipsychotics + Uses, Types & Side Effects |url=https://www.drugs.com/drug-class/atypical-antipsychotics.html |website=Drugs.com |accessdate=22 April 2021 |language=en}}</ref> ଏହି ଔଷଧ ଗୁଡ଼ିକ ପାଟିରେ କିମ୍ବା ମାଂସପେଶୀରେ ଇଞ୍ଜେକ୍ସନ ଦ୍ୱାରା ନିଆଯାଇପାରେ | <ref name="Hitch2019">{{Cite book|last=Hitchings|first=Andrew|url=https://books.google.com/books?id=FPx0DwAAQBAJ|title=The Top 100 Drugs: Clinical Pharmacology and Practical Prescribing|last2=Lonsdale|first2=Dagan|last3=Burrage|first3=Daniel|last4=Baker|first4=Emma|date=2019|publisher=Elsevier|isbn=978-0-7020-7442-4|edition=2nd|pages=80|language=en}}</ref> <ref name="Stat2021">{{cite journal |last1=Willner |first1=K |last2=Vasan |first2=S |last3=Abdijadid |first3=S |title=Atypical Antipsychotic Agents |date=January 2021 |pmid=28846323}}</ref> ଦୀର୍ଘକାଳୀନ ଇଞ୍ଜେକସନ ମଧ୍ୟ ଉପଲବ୍ଧ | <ref name="Stat2021">{{cite journal |last1=Willner |first1=K |last2=Vasan |first2=S |last3=Abdijadid |first3=S |title=Atypical Antipsychotic Agents |date=January 2021 |pmid=28846323}}</ref>

ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ନିଦ୍ରାଳୁ ଦୋଷ, ଓଜନ ବୃଦ୍ଧି, [[ମଧୁମେହ]], ଯୌନ‌କ୍ରିୟା ଅସୁବିଧା ଓ ଅନିଚ୍ଛାକୃତ ଚଳନ ବ୍ୟାଧି ହୋଇପାରେ କିନ୍ତୁ ଶେଷୋକ୍ତ ଅସୁବିଧା ସ୍ୱାଭାବିକ ଆଣ୍ଟିସାଇକୋଟିକ ତୁଳନାରେ କମ୍ ଦେଖାଯାଏ | <ref name="Hitch2019">{{Cite book|last=Hitchings|first=Andrew|url=https://books.google.com/books?id=FPx0DwAAQBAJ|title=The Top 100 Drugs: Clinical Pharmacology and Practical Prescribing|last2=Lonsdale|first2=Dagan|last3=Burrage|first3=Daniel|last4=Baker|first4=Emma|date=2019|publisher=Elsevier|isbn=978-0-7020-7442-4|edition=2nd|pages=80|language=en}}</ref> ଅନ୍ୟାନ୍ୟ ଗମ୍ଭୀର ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ [[ନିଉରୋଲେପ୍ଟିକ ମାଲିଗନାଣ୍ଟ ସିଣ୍ଡ୍ରୋମ|ନ୍ୟୁରୋଲେପ୍ଟିକ୍ ମାଲିଗନାଣ୍ଟ ସିଣ୍ଡ୍ରୋମ]] ଏବଂ [[ଲଙ୍ଗ କ୍ୟୁଟି ସିଣ୍ଡ୍ରୋମ]] ହୋଇପାରେ। <ref name="Stat2021">{{cite journal |last1=Willner |first1=K |last2=Vasan |first2=S |last3=Abdijadid |first3=S |title=Atypical Antipsychotic Agents |date=January 2021 |pmid=28846323}}</ref> [[କ୍ଲୋଜାପିନ|କ୍ଲିଜାପିନ]] ଯୋଗୁ କମ ଶ୍ୱେତ ରକ୍ତକଣିକା ଓ ହୃତ୍‌ପିଣ୍ଡ ପ୍ରଦାହ ହୋଇପାରେ । <ref name="Hitch2019">{{Cite book|last=Hitchings|first=Andrew|url=https://books.google.com/books?id=FPx0DwAAQBAJ|title=The Top 100 Drugs: Clinical Pharmacology and Practical Prescribing|last2=Lonsdale|first2=Dagan|last3=Burrage|first3=Daniel|last4=Baker|first4=Emma|date=2019|publisher=Elsevier|isbn=978-0-7020-7442-4|edition=2nd|pages=80|language=en}}</ref> ଡିମେନ୍ସିଆ ଥିଲେ ମୃତ୍ୟୁ ଆଶଙ୍କା ଅଧିକ ହୁଏ । <ref name="Stat2021">{{cite journal |last1=Willner |first1=K |last2=Vasan |first2=S |last3=Abdijadid |first3=S |title=Atypical Antipsychotic Agents |date=January 2021 |pmid=28846323}}</ref> ଡୋପାମାଇନ୍ ଏବଂ ସେରୋଟୋନିନ ପାଇଁ ମସ୍ତିଷ୍କରେ ଥିବା ରିସେପ୍ଟର ଗୁଡ଼ିକୁ ଅବରୋଧ କରି କାର୍ଯ୍ୟକ୍ଷମ ହୁଅନ୍ତି | <ref name="Stat2021">{{cite journal |last1=Willner |first1=K |last2=Vasan |first2=S |last3=Abdijadid |first3=S |title=Atypical Antipsychotic Agents |date=January 2021 |pmid=28846323}}</ref>

୧୯୭୦ ଦଶକରେ ଆଟିପିକାଲ୍ ଆଣ୍ଟିସାଇକୋଟିକ୍ସ ଔଷଧ ଗୁଡ଼ିକ ଡାକ୍ତରୀ ବ୍ୟବହାରରେ ଆସିଥିଲା | <ref name="Ari2018">{{Cite journal|displayauthors=6|vauthors=Aringhieri S, Carli M, Kolachalam S, Verdesca V, Cini E, Rossi M, McCormick PJ, Corsini GU, Maggio R, Scarselli M|date=December 2018|title=Molecular targets of atypical antipsychotics: From mechanism of action to clinical differences|journal=Pharmacology & Therapeutics|volume=192|pages=20–41|doi=10.1016/j.pharmthera.2018.06.012|pmid=29953902}}</ref> ଏମାନଙ୍କ ମଧ୍ୟରୁ କେତେକ ଔଷଧ ଜେନେରିକ ନାମରେ ଉପଲବ୍ଧ ଏବଂ ଅପେକ୍ଷାକୃତ ଶସ୍ତା | <ref name="Hitch2019">{{Cite book|last=Hitchings|first=Andrew|url=https://books.google.com/books?id=FPx0DwAAQBAJ|title=The Top 100 Drugs: Clinical Pharmacology and Practical Prescribing|last2=Lonsdale|first2=Dagan|last3=Burrage|first3=Daniel|last4=Baker|first4=Emma|date=2019|publisher=Elsevier|isbn=978-0-7020-7442-4|edition=2nd|pages=80|language=en}}</ref> ୨୦୧୮ ମସିହାରେ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ୟୁନାଇଟେଡ୍ ଷ୍ଟାଟସ୍ ରେ [[କୋଟିଆପିନ]] ୫୯ ତମ ସର୍ବାଧିକ ପ୍ରେସକ୍ରିପସନ ହୋଇଥିବା ଔଷଧ ଏବଂ [[ଆରିପିପ୍ରାଜଲ|ଆରିପିପ୍ରାଜୋଲ୍]] ୧୦୧ତମ ସର୍ବାଧିକ ପ୍ରେସକ୍ରିପସନ ଔଷଧ ଥିଲା | <ref>{{Cite web|url=https://clincalc.com/DrugStats/Top300Drugs.aspx|title=The Top 300 of 2021|website=clincalc.com|access-date=22 April 2021}}</ref>