"ପିତ୍ତକୋଷ" ପୃଷ୍ଠାର ସଂସ୍କରଣ‌ଗୁଡ଼ିକ ମଧ୍ୟରେ ତଫାତ

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ଅଧିକ ତ‌ଥ୍ୟ ଦିଆଗଲା
ଅଧିକ ତ‌ଥ୍ୟ ଦିଆଗଲା
୨୭ କ ଧାଡ଼ି:
 
== କାର୍ଯ୍ୟ ==
{{ପିତ୍ତ ନଳୀ ଓ ଅଗ୍ନାଶୟ}}
 
ନିଜ ଅଙ୍ଗରେ ପିତ୍ତ ([[:en:bile|bile]]) ବା ଗଲ୍ ଜମାକରି ରଖିବା ପିତ୍ତାଶୟର ମୂଳ କାର୍ଯ୍ୟ ଯାହା ଖାଦ୍ୟରେ ଥିବା ଚର୍ବି ଜାତୀୟ ଅଂଶକୁ ହଜମ କରିବାରେ ସାହାଯ୍ୟ କରେ । ଯକୃତରେ ସୃଷ୍ଟି ହେବା ପରେ କ୍ଷୁଦ୍ର ନଳୀ ମଧରେ ପିତ୍ତ ବୋହିଯାଇ ସିସ୍ଟିକ ଡକ୍ଟ ଓ ତା'ପରେ ବଡ଼ ହେପାଟିକ ଡକ୍ଟରେ ଯାଇ ପିତ୍ତାଶୟରେ ଜମା ହୁଏ । ଯେ କୌଣସି ଏକ ସମୟରେ ସେଥିରେ ପ୍ରାୟ ୩୦ରୁ ୬୦ ମି:ଲି: ପିତ୍ତ ଜମାହୋଇ ରହେ । {{^| Produced by the liver, bile flows through small vessels into the larger [[hepatic duct]]s and ultimately through the [[cystic duct]] (parts of the [[biliary tree]]) into the gallbladder, where it is stored. At any one time, {{convert|30|to|60|ml|usoz}} of bile is stored within the gallbladder.<ref name=PHYSIOLOGY2005 />
 
ଚର୍ବି‌ଯୁକ୍ତ ଖାଦ୍ୟ ପାକଅନ୍ତନଳୀ ମଣ୍ଡଳରେ ପ୍ରବେଶ କଲେ ଡୁଓଡେନନ ଓ ଜେଜୁନମ ଭିତରେ ଥିବା ଆଇ କୋଷ ମଧ୍ୟରୁ କୋଲିସିସ୍ଟୋକାଇନିନ ନିର୍ଗତ ହୁଏ । ପିତ୍ତକୋଷରେ କୋଲିସିସ୍ଟିକାଇନିନ ଉତ୍ତେଜନା ସୃଷ୍ଟି କରିବାଦ୍ୱାରା ପିତ୍ତକୋଷ ବାରମ୍ବାର ସଙ୍କୁଚିତ ଓ ପ୍ରସାରିତ ହୋଇ ଏହା ଭିତରେ ଥିବା ପଦାର୍ଥକୁ କମନ ବାଇଲ ଡକ୍ଟ ଭିତର ଦେଇ ଶେଷରେ ଡୁଓଡେନମ ଭିତରକୁ ଛାଡ଼େ । ଆଂଶିକ ହଜମ ହୋଇଥିବା ଚର୍ବିକୁ ପିତ୍ତ ଇମଲସିଫାଇ କରିବାଦ୍ୱାରା ତାହାର ଅବଶୋଷଣ ହୋଇଯାଏ । ପିତ୍ତରେ ଜଳ ଓ ବାଇଲ ଲବଣ ଥାଏ ଓ ଏହା ହେମୋଗ୍ଲୋବିନର ମେଟାବୋଲିଜ୍ମ ଯୋଗୁ ସୃଷ୍ଟି ହେଉଥିବା ବିଲିରୁବିନ ଦେହରର ବିଦାୟ କରିବାରେ ସାହାଯ୍ୟ କରେ । <ref name=PHYSIOLOGY2005 />
When food containing fat enters the [[Gastrointestinal tract|digestive tract]], it stimulates the [[secretion]] of [[cholecystokinin]] (CCK) from [[I cell]]s of the duodenum and jejunum. In response to cholecystokinin, the gallbladder rhythmically contracts and releases its contents into the [[common bile duct]], eventually draining into the [[duodenum]]. The bile [[Emulsion|emulsifies]] fats in partly digested food, thereby assisting their absorption. Bile consists primarily of water and [[bile salt]]s, and also acts as a means of eliminating [[bilirubin]], a product of [[hemoglobin]] metabolism, from the body.<ref name=PHYSIOLOGY2005 />
 
Theଯକୃତରୁ bileନିର୍ଗତ thatହୋଇଥିବା isପିତ୍ତ, secretedପିତ୍ତକୋଷରୁ byନିର୍ଗତ theହେଉଥିବା liverପିତ୍ତ andସ‌ହିତ storedସମାନ inନୁହେଁ the gallbladderପିତ୍ତକୋଷରେ isଏହା notପୁର୍ବାପେକ୍ଷା the୩ରୁ same୧୦ asଗୁଣ the bile that is secreted by the gallbladder. During gallbladder storage of bile, it is concentrated 3-10ଗାଢ଼ foldହୋଇଯାଏ<ref>{{Cite web|url=https://www.cghjournal.org/article/S1542-3565(05)00369-1/pdf|title=Biliary Sludge Is Formed by Modification of Hepatic Bile by the Gallbladder Mucosa|last=KO|first=CYNTHIA|date=2005|website=CLINICAL GASTROENTEROLOGY AND HEPATOLOGY}}</ref> by removalଏହା ofଜଳ someସ‌ହିତ waterକିଛି andଇଲେକ୍ଟ୍ରୋଲାଇଟ electrolytes.ବିଦାୟ Thisକରିଦେବା isଯୋଗୁ throughସମ୍ଭବ theହୁଏ [[active transport]]ଜଳ of sodiumକ୍ଲୋରାଇଡ andଆୟନର ଆକ୍ଟିଭ ଟ୍ରାନ୍ସପୋର୍ଟ ଯୋଗୁ ଏହା ହୁଏ । chloride ions<ref>{{Cite journal|last=Meyer|first=G.|last2=Guizzardi|first2=F.|last3=Rodighiero|first3=S.|last4=Manfredi|first4=R.|last5=Saino|first5=S.|last6=Sironi|first6=C.|last7=Garavaglia|first7=M. L.|last8=Bazzini|first8=C.|last9=Bottà|first9=G.|date=June 2005|title=Ion transport across the gallbladder epithelium|journal=Current Drug Targets. Immune, Endocrine and Metabolic Disorders|volume=5|issue=2|pages=143–151|issn=1568-0088|pmid=16089346|doi=10.2174/1568008054064805}}</ref> across the epithelium of the gallbladder, which creates an [[osmotic pressure]] that also causes water and other electrolytes to be reabsorbed.<ref name=PHYSIOLOGY2005>{{cite book|last=Hall|first=Arthur C. Guyton, John E.|title=Textbook of medical physiology|year=2005|publisher=W.B. Saunders|location=Philadelphia|isbn=978-0-7216-0240-0|pages=802–804|edition=11th}}</ref>
 
The bile that is secreted by the liver and stored in the gallbladder is not the same as the bile that is secreted by the gallbladder. During gallbladder storage of bile, it is concentrated 3-10 fold<ref>{{Cite web|url=https://www.cghjournal.org/article/S1542-3565(05)00369-1/pdf|title=Biliary Sludge Is Formed by Modification of Hepatic Bile by the Gallbladder Mucosa|last=KO|first=CYNTHIA|date=2005|website=CLINICAL GASTROENTEROLOGY AND HEPATOLOGY}}</ref> by removal of some water and electrolytes. This is through the [[active transport]] of sodium and chloride ions<ref>{{Cite journal|last=Meyer|first=G.|last2=Guizzardi|first2=F.|last3=Rodighiero|first3=S.|last4=Manfredi|first4=R.|last5=Saino|first5=S.|last6=Sironi|first6=C.|last7=Garavaglia|first7=M. L.|last8=Bazzini|first8=C.|last9=Bottà|first9=G.|date=June 2005|title=Ion transport across the gallbladder epithelium|journal=Current Drug Targets. Immune, Endocrine and Metabolic Disorders|volume=5|issue=2|pages=143–151|issn=1568-0088|pmid=16089346|doi=10.2174/1568008054064805}}</ref> across the epithelium of the gallbladder, which creates an [[osmotic pressure]] that also causes water and other electrolytes to be reabsorbed.<ref name=PHYSIOLOGY2005>{{cite book|last=Hall|first=Arthur C. Guyton, John E.|title=Textbook of medical physiology|year=2005|publisher=W.B. Saunders|location=Philadelphia|isbn=978-0-7216-0240-0|pages=802–804|edition=11th}}</ref>
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== ଆଧାର ==
{{ଆଧାର}}
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