ଆଲମୋଟ୍ରିପଟାନ

ଆଲମୋଟ୍ରିପଟାନ
Clinical data
Trade names	Axert
Synonyms	Almotriptan hydrogen malate
AHFS/Drugs.com	monograph
MedlinePlus	a603028
data	US DailyMed: Almotriptan;
Routes of; administration	By mouth
Legal status
Legal status	UK: POM (Prescription only) ; US: ℞-only ; EU: Rx-only ; ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	70%
Protein binding	35%
Metabolism	Liver
Elimination half-life	3–4 hours
Identifiers
	IUPAC name N,N-dimethyl-2- [5-(pyrrolidin-1-ylsulfonylmethyl)- 1H-indol-3-yl]-ethanamine;
Chemical and physical data
Formula	C17H25N3O2S
Molar mass	୩୩୫.୪୭ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN(C)CCc2c[nH]c3ccc(CS(=O)(=O)N1CCCC1)cc23;
	InChI InChI=1S/C17H25N3O2S/c1-19(2)10-7-15-12-18-17-6-5-14(11-16(15)17)13-23(21,22)20-8-3-4-9-20/h5-6,11-12,18H,3-4,7-10,13H2,1-2H3 ; Key:WKEMJKQOLOHJLZ-UHFFFAOYSA-N ;
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ଆଲମୋଟ୍ରିପଟାନ (ବିକ୍ରୟନାମ ଆକ୍ସର୍ଟ ଇତ୍ୟାଦି), ଏକ ଔଷଧ ଯାହା ଅଧକପାଳି ମୁଣ୍ଡବିନ୍ଧାର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ । ^[୧] ^[୫] ୧୧ ବର୍ଷ ବୟସରୁ ଅଧିକ ଲୋକଙ୍କଠାରେ ବ୍ୟବହୃତ ହୋଇପାରେ । କ୍ଲଷ୍ଟର ମୁଣ୍ଡବିନ୍ଧା ପାଇଁ ଏହା କେତେଦୂର ଫଳପ୍ରଦ ତାହାର ପ୍ରମାଣ ଅଭାବ ଅଛି । ^[୫] ଏହା ପାଟିରେ ଦିଆଯାଏ । ^[୧]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଅଇ, ଶୁଖିଲା ପାଟି, ନିଦ୍ରାଳୁ ଭାବ ଏବଂ କାଲୁଆ ହୋଇପାରେ ।^[୬] ଅନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ହୃତ୍‌ପିଣ୍ଡ ସମସ୍ୟା, ଷ୍ଟ୍ରୋକ, ରେନଡ ସିଣ୍ଡ୍ରୋମ, ସେରୋଟୋନିନ୍ ସିଣ୍ଡ୍ରୋମ ଏବଂ ଔଷଧର ଅତ୍ୟଧିକ ବ୍ୟବହାର ଯୋଗୁ ମୁଣ୍ଡବିନ୍ଧା ହୋଇପାରେ । ^[୬] ଗର୍ଭାବସ୍ଥାରେ ବ୍ୟବହାର ଶିଶୁର କ୍ଷତି କରିପାରେ । ^[୬] ଏହା ଏକ ଟ୍ରିପ୍ଟାନ ଶ୍ରେଣୀ ଅନ୍ତର୍ଭୁକ୍ତ । ^[୧]

୧୯୯୨ ମସିହାରେ ଆଲମୋଟ୍ରିପଟାନ ପେଟେଣ୍ଟ କରାଯାଇଥିଲା ଏବଂ ୨୦୦୦ରେ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ ଅନୁମୋଦିତ ହୋଇଥିଲା ।^[୭] ଏହା ଏକ ସାଧାରଣ ଔଷଧ ଭାବରେ ଉପଲବ୍ଧ । ^[୧] ଯୁକ୍ତରାଜ୍ୟରେ ୨୦୨୧ ସୁଦ୍ଧା ଏକ ମାତ୍ରା ଔଷଧ ପାଇଁ ପ୍ରାୟ ୨.୮୦ ପାଉଣ୍ଡ ଖର୍ଚ୍ଚ ହୋଇଥାଏ। ^[୧] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହି ପରିମାଣର ମୂଲ୍ୟ ପ୍ରାୟ $୯ ଡଲାର ଅଟେ। ^[୮]

ଆଧାର

↑ ^୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ ^୧.୫ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 500. ISBN 978-0857114105.
↑ "Archive copy" (PDF). Archived (PDF) from the original on 2021-11-05. Retrieved 2021-02-18.{{cite web}}: CS1 maint: archived copy as title (link)
↑ "Almotriptan tablet, film coated". DailyMed. Archived from the original on 24 March 2021. Retrieved 17 February 2021.
↑ "Axert- almotriptan malate tablet, coated". DailyMed. Archived from the original on 23 March 2021. Retrieved 17 February 2021.
↑ ^୫.୦ ^୫.୧ "Almotriptan Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 23 January 2021. Retrieved 14 January 2022.
↑ ^୬.୦ ^୬.୧ ^୬.୨ "DailyMed - ALMOTRIPTAN MALATE- almotriptan tablet, film coated". dailymed.nlm.nih.gov. Archived from the original on 22 March 2021. Retrieved 14 January 2022.
↑ Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 531. ISBN 9783527607495. Archived from the original on 2020-10-23. Retrieved 2021-02-18. {{cite book}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
↑ "Almotriptan Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 14 June 2016. Retrieved 14 January 2022.

[BNF81-1] ୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ ^୧.୫ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 500. ISBN 978-0857114105.

[2] "Archive copy" (PDF). Archived (PDF) from the original on 2021-11-05. Retrieved 2021-02-18.{{cite web}}: CS1 maint: archived copy as title (link)

[3] "Almotriptan tablet, film coated". DailyMed. Archived from the original on 24 March 2021. Retrieved 17 February 2021.

[Axert_FDA_label-4] "Axert- almotriptan malate tablet, coated". DailyMed. Archived from the original on 23 March 2021. Retrieved 17 February 2021.

[AHFS2022-5] ୫.୦ ^୫.୧ "Almotriptan Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 23 January 2021. Retrieved 14 January 2022.

[PI2022-6] ୬.୦ ^୬.୧ ^୬.୨ "DailyMed - ALMOTRIPTAN MALATE- almotriptan tablet, film coated". dailymed.nlm.nih.gov. Archived from the original on 22 March 2021. Retrieved 14 January 2022.

[Fis2006-7] Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 531. ISBN 9783527607495. Archived from the original on 2020-10-23. Retrieved 2021-02-18. {{cite book}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)

[8] "Almotriptan Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 14 June 2016. Retrieved 14 January 2022.

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