ସେଭିମେଲାଇନ

ସେଭିମେଲାଇନ
Clinical data
Pronunciation	se vim' e leen
Trade names	Evoxac
AHFS/Drugs.com	monograph
MedlinePlus	a608025
Pregnancy; category	C;
Routes of; administration	By mouth (capsules)
Legal status
Legal status	℞ (Prescription only);
Pharmacokinetic data
Protein binding	<20%
Identifiers
	IUPAC name (2R,2R)-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane];
Chemical and physical data
Formula	C10H17NOS
Molar mass	୧୯୯.୩୧ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O1[C@H](SC[C@@]12CN3CCC2CC3)C;
	InChI InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3/t8-,10-/m1/s1 ; Key:WUTYZMFRCNBCHQ-PSASIEDQSA-N ;
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ସେଭିମେଲାଇନ, ବେପାର ନାମ ଇଭୋକ୍ସାକ୍, ଏକ ଔଷଧ ଯାହା ଜୋଗ୍ରାନ ସିଣ୍ଡ୍ରୋମ କିମ୍ବା ବିକିରଣ ଚିକିତ୍ସା ଜନିତ ଶୁଖିଲା ପାଟିର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ।^[୧] ଏହା ପାଇକାର୍ପିନ ସହିତ ଏକ ସମାନ । ^[୨] ଏହା ପାଟିରେ ଦିଆଯାଏ । ^[୧],

ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟା ସାଧାରଣତଃ ସାମାନ୍ୟ ହୁଏ ଏବଂ ଏଥିରେ ବର୍ଦ୍ଧିତ ଝାଳ, ନାକରୁ ପାଣି ପ୍ରବାହିତ, ଅଇ, ତରଳ ଝାଡ଼ା, ମୁଣ୍ଡବିନ୍ଧା, ମୁଣ୍ଡ ବୁଲାଇବା, ଦୃଷ୍ଟି ବ୍ୟାଘାତ ଏବଂ ଥକ୍କାପଣ ହୋଇପାରେ । ^[୧] ଗର୍ଭାବସ୍ଥାରେ ସୁରକ୍ଷା ଅସ୍ପଷ୍ଟ ଅଟେ। ^[୨] ଏହା ଏକ ମସ୍କାରିନିକ୍ ଆଗୋନିଷ୍ଟ, ଯାହାଦ୍ୱାରା ଲାଳ ଉତ୍ପାଦନ ବୃଦ୍ଧି ପାଇଥାଏ | ^[୧]

୨୦୦୦ ମସିହାରେ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ ସେଭିମେଲାଇନ ଅନୁମୋଦିତ ହୋଇଥିଲା। ^[୨] ଏହା ଏକ ସାଧାରଣ ଔଷଧ ଭାବରେ ଉପଲବ୍ଧ । ^[୩] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ୨୦୨୧ ସୁଦ୍ଧା ଏକ ମାସ ଔଷଧର ମୂଲ୍ୟ ପ୍ରାୟ ୫୨ ଡଲାର ଅଟେ ।^[୩]

ଆଧାର

↑ ^୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ "Cevimeline". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. 2012. Archived from the original on 6 May 2021. Retrieved 3 January 2022.
↑ ^୨.୦ ^୨.୧ ^୨.୨ "Cevimeline Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Retrieved 3 January 2022.
↑ ^୩.୦ ^୩.୧ "Cevimeline Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 26 September 2016. Retrieved 3 January 2022.

[Liv2021-1] ୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ "Cevimeline". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. 2012. Archived from the original on 6 May 2021. Retrieved 3 January 2022.

[AHFS2022-2] ୨.୦ ^୨.୧ ^୨.୨ "Cevimeline Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Retrieved 3 January 2022.

[GX2022-3] ୩.୦ ^୩.୧ "Cevimeline Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 26 September 2016. Retrieved 3 January 2022.

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Clinical data


Pronunciation	se vim' e leen^[୧]
Trade names	Evoxac
AHFS/Drugs.com	monograph
MedlinePlus	a608025
Pregnancy category	C
Routes of administration	By mouth (capsules)
Legal status
Legal status	℞ (Prescription only)
Pharmacokinetic data
Protein binding	<20%
Identifiers
IUPAC name (2R,2R)-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]
Chemical and physical data
Formula	C₁₀H₁₇NOS
Molar mass	୧୯୯.୩୧ g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O1[C@H](SC[C@@]12CN3CCC2CC3)C
InChI InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3/t8-,10-/m1/s1^Y Key:WUTYZMFRCNBCHQ-PSASIEDQSA-N^Y
(verify)