ପଲିଡୋକାନୋଲ

ପଲିଡୋକାନୋଲ
Clinical data
Synonyms	Polydocanol; Laureth 9; Macrogol lauryl ether; Lauromacrogol; PEG-9 lauryl alcohol; POE-9 lauryl alcohol; Dodecylpolyethyleneglycolether; Hydroxyl polyethoxy dodecane; Oxypolyethoxydodecane;
AHFS/Drugs.com	monograph
Routes of; administration	Injection into a vein
Legal status
Legal status	OTC (topical), ℞ (injection);
Identifiers
	IUPAC name 3,6,9,12,15,18,21,24,27-nonaoxanonatriacontan-1-ol;
ECHA InfoCard	100.019.351
Chemical and physical data
Formula	C30H62O10
Molar mass	୫୮୨.୮୨ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO;
	InChI InChI=1S/C30H62O10/c1-2-3-4-5-6-7-8-9-10-11-13-32-15-17-34-19-21-36-23-25-38-27-29-40-30-28-39-26-24-37-22-20-35-18-16-33-14-12-31/h31H,2-30H2,1H3 ; Key:ONJQDTZCDSESIW-UHFFFAOYSA-N ;
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ପଲିଡୋକାନୋଲ, ଆସ୍କ୍ଲେରା ହେଉଛି ଏକ ବେପାର ନାମ, ଏକ ଔଷଧ ଯାହା ସ୍ପାଇଡର ଶିରା ଏବଂ ରେଟିକୁଲାର ଶିରା ଓ ଭେରିକଜ ଶିରା ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ।^[୧] ଏହା ହେମାଞ୍ଜିଓଓମା ଏବଂ ଭାସ୍କୁଲାର ବିକୃତି ପାଇଁ ମଧ୍ୟ ବ୍ୟବହୃତ ହୋଇପାରେ ।^[୨] ସ୍କ୍ଲେରୋଥେରାପିର ଏକ ଅଂଶ ଭାବରେ ଏହା ଶିରାରେ ଇଞ୍ଜେକସନ ଆକାରରେ ଦିଆଯାଏ ।^[୩]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଏକ ସାମାନ୍ୟ ସ୍ଥାନୀୟ ପ୍ରତିକ୍ରିୟା ହୋଇପାରେ ।^[୧] ଅନ୍ୟାନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଆନାଫାଇଲାକ୍‌ସିସ, ରକ୍ତ ଜମାଟ ବାନ୍ଧିବା ଏବଂ ତନ୍ତୁ କ୍ଷୟ ହୋଇପାରେ | ^[୧] ଏହା ଏକ ନନ୍‌ଆୟୋନିକ୍ ଡିଟରଜେଣ୍ଟ ।^[୩]

୨୦୧୦ରେ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ ପଲିଡୋକାନୋଲକୁ ଅନୁମୋଦନ କରାଯାଇଥିଲା ।^[୧] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ପଲିଡୋକାନୋଲର ୨ ମିଲି ଦ୍ରବର ମୂଲ୍ୟ ୨୦୨୧ ସୁଦ୍ଧା ପ୍ରାୟ ୨୨ ଡଲାର ଥିଲା । ^[୪] ଏହା ପ୍ରସାଧନ ସାମଗ୍ରୀରେ ମଧ୍ୟ ବ୍ୟବହୃତ ହୁଏ ।^[୫]

ଆଧାର

↑ ^୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ "DailyMed - ASCLERA- polidocanol injection, solution". dailymed.nlm.nih.gov. Archived from the original on 24 March 2021. Retrieved 28 October 2021.
↑ Gao Z, Zhang Y, Li W, Shi C (January 2018). "Effectiveness and safety of polidocanol for the treatment of hemangiomas and vascular malformations: A meta-analysis". Dermatologic Therapy. 31 (1). doi:10.1111/dth.12568. PMID 29082587.
↑ ^୩.୦ ^୩.୧ "Polidocanol Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 May 2016. Retrieved 28 October 2021.
↑ "Asclera Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Retrieved 28 October 2021.
↑ "ADDENDUM to the SCCP opinion on polidocanol (SCCP/1130/07)" (PDF). Archived (PDF) from the original on 14 June 2015. Retrieved 28 October 2021.

[PI2021-1] ୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ "DailyMed - ASCLERA- polidocanol injection, solution". dailymed.nlm.nih.gov. Archived from the original on 24 March 2021. Retrieved 28 October 2021.

[Gao_2018-2] Gao Z, Zhang Y, Li W, Shi C (January 2018). "Effectiveness and safety of polidocanol for the treatment of hemangiomas and vascular malformations: A meta-analysis". Dermatologic Therapy. 31 (1). doi:10.1111/dth.12568. PMID 29082587.

[AHFS2021-3] ୩.୦ ^୩.୧ "Polidocanol Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 May 2016. Retrieved 28 October 2021.

[4] "Asclera Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Retrieved 28 October 2021.

[5] "ADDENDUM to the SCCP opinion on polidocanol (SCCP/1130/07)" (PDF). Archived (PDF) from the original on 14 June 2015. Retrieved 28 October 2021.

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Clinical data

Synonyms	Polydocanol Laureth 9 Macrogol lauryl ether Lauromacrogol PEG-9 lauryl alcohol POE-9 lauryl alcohol Dodecylpolyethyleneglycolether Hydroxyl polyethoxy dodecane Oxypolyethoxydodecane
AHFS/Drugs.com	monograph
Routes of administration	Injection into a vein
Legal status
Legal status	OTC (topical), ℞ (injection)
Identifiers
IUPAC name 3,6,9,12,15,18,21,24,27-nonaoxanonatriacontan-1-ol
ECHA InfoCard	100.019.351
Chemical and physical data
Formula	C₃₀H₆₂O₁₀
Molar mass	୫୮୨.୮୨ g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
InChI InChI=1S/C30H62O10/c1-2-3-4-5-6-7-8-9-10-11-13-32-15-17-34-19-21-36-23-25-38-27-29-40-30-28-39-26-24-37-22-20-35-18-16-33-14-12-31/h31H,2-30H2,1H3^N Key:ONJQDTZCDSESIW-UHFFFAOYSA-N^N
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