ମିଟାପିଭାଟ

ମିଟାପିଭାଟ
Clinical data
Trade names	Pyrukynd
Synonyms	AG-348
AHFS/Drugs.com	monograph
data	US DailyMed: Mitapivat;
Routes of; administration	By mouth
Legal status
Legal status	US: ℞-only ; EU: Rx-only ;
Chemical and physical data
Formula	C24H26N4O3S
Molar mass	୪୫୦.୫୬ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N1CCN(CC2CC2)CC1)C1=CC=C(NS(=O)(=O)C2=CC=CC3=C2N=CC=C3)C=C1;
	InChI InChI=1S/C24H26N4O3S/c29-24(28-15-13-27(14-16-28)17-18-6-7-18)20-8-10-21(11-9-20)26-32(30,31)22-5-1-3-19-4-2-12-25-23(19)22/h1-5,8-12,18,26H,6-7,13-17H2; Key:XAYGBKHKBBXDAK-UHFFFAOYSA-N;

ମିଟାପିଭାଟ (ଇଂରାଜୀ ଭାଷାରେ Mitapivat), ପିରୁକିଣ୍ଡ ବିକ୍ରୟ ନାମ, ହେଉଛି ଏକ ଔଷଧ ଯାହା ପାଇରୁଭେଟ କାଇନେଜ ଅଭାବ ଥିବା ହେମୋଲାଇଟିକ ରକ୍ତହୀନତାର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ । ^[୨] ଏହା ବୟସ୍କମାନଙ୍କ ପାଇଁ ଅନୁମୋଦିତ ।^[୧] ଏହା ପାଟିରେ ଦିଆଯାଏ | ^[୨]

ଟାସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଶୋଇବାରେ ଅସୁବିଧା, ପିଠି ଯନ୍ତ୍ରଣା, ଅଇ, ଏବଂ ଗଣ୍ଠି ଯନ୍ତ୍ରଣା ହୋଇପାରେ ।^[୨] ^[୧] ଗର୍ଭାବସ୍ଥାରେ ସୁରକ୍ଷା ଅସ୍ପଷ୍ଟ ଅଟେ ।| ^[୨] ଏହା ଏକ ପାଇରୁଭେଟ କାଇନେଜ ସକ୍ରିୟକାରୀ ବା ଆକ୍ଟିଭେଟର୍ ।^[୨]

୨୦୨୨ ମସିହାରେ ଆମେରିକା ଏବଂ ୟୁରୋପରେ ଡାକ୍ତରୀ ବ୍ୟବହାର ପାଇଁ ମିଟାପିଭାଟକୁ ଅନୁମୋଦନ କରାଯାଇଥିଲା ^[୨] ^[୧] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ୪ ସପ୍ତାହର ଚିକିତ୍ସା ସୁଦ୍ଧା ପ୍ରାୟ ୨୭,୦୦୦ଡଲାର ଅଟେ ^[୩] ୨୦୨୨2 ସୁଦ୍ଧା ବ୍ରିଟେନରେ ଏହା ବ୍ୟବସାୟିକ ଭାବରେ ଉପଲବ୍ଧ ନୁହେଁ ^[୪]

ଆଧାର

↑ ^୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ "Pyrukynd EPAR". European Medicines Agency (EMA). 14 September 2022. Archived from the original on 6 December 2022. Retrieved 5 December 2022. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
↑ ^୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ ^୨.୪ ^୨.୫ ^୨.୬ "Pyrukynd- mitapivat tablet, film coated Pyrukynd- mitapivat kit". DailyMed. 23 February 2022. Archived from the original on 3 March 2022. Retrieved 3 March 2022.
↑ "Pyrukynd Prices, Coupons, Copay & Patient Assistance". Drugs.com (in ଇଂରାଜୀ). Retrieved 11 December 2022.
↑ "Mitapivat". SPS - Specialist Pharmacy Service. 3 November 2019. Archived from the original on 12 August 2022. Retrieved 11 December 2022.

[EPAR2022-1] ୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ "Pyrukynd EPAR". European Medicines Agency (EMA). 14 September 2022. Archived from the original on 6 December 2022. Retrieved 5 December 2022. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.

[PI2022-2] ୨.୦ ^୨.୧ ^୨.୨ ^୨.୩ ^୨.୪ ^୨.୫ ^୨.୬ "Pyrukynd- mitapivat tablet, film coated Pyrukynd- mitapivat kit". DailyMed. 23 February 2022. Archived from the original on 3 March 2022. Retrieved 3 March 2022.

[3] "Pyrukynd Prices, Coupons, Copay & Patient Assistance". Drugs.com (in ଇଂରାଜୀ). Retrieved 11 December 2022.

[4] "Mitapivat". SPS - Specialist Pharmacy Service. 3 November 2019. Archived from the original on 12 August 2022. Retrieved 11 December 2022.

[୨]

[୧]

[୩]

[୪]