ବ୍ରୋମଫେନିରାମିନ

ବ୍ରୋମଫେନିରାମିନ
Clinical data
Trade names	Bromfed, Dimetapp, Bromfenex, and others
AHFS/Drugs.com	monograph
MedlinePlus	a682545
Pregnancy; category	US: C (Risk not ruled out) ; ;
Routes of; administration	By mouth
Legal status
Legal status	AU: S4 / S3 / S2 ; US: Rx-only / OTC ; Unscheduled, OTC;
Pharmacokinetic data
Metabolism	Liver
Elimination half-life	24.9 ± 9.3 hours
Duration of action	48 hrs
Excretion	Urine
Identifiers
	IUPAC name (R/S)-3-(4-Bromophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine;
ECHA InfoCard	100.001.507
Chemical and physical data
Formula	C16H19BrN2
Molar mass	୩୧୯.୨୫ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Brc1ccc(cc1)C(c2ncccc2)CCN(C)C;
	InChI InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3 ; Key:ZDIGNSYAACHWNL-UHFFFAOYSA-N ;
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ନାମ

ବ୍ରୋମଫେନିରାମିନ, ଏକ ବେପାର ନାମ ଡିମେଟାପ, ^[୪] ହେଉଛି ଏକ ଆଣ୍ଟିହିଷ୍ଟାମିନ ଯାହା ସାଧାରଣ ଥଣ୍ଡା ଏବଂ ଆଲର୍ଜି ରାଇନାଇଟିସର ଲକ୍ଷଣ ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ଯେପରିକି ନାକରୁ ଅଧିକ ପାଣି ବୋହିବା, ଆଖିରୁ ପାଣି ବୋହିବା ଓ ଛିଙ୍କ ହେବା । ^[୫] ୧ ବର୍ଷରୁ କମ୍ ପିଲାମାନଙ୍କଠାରେ ଏହାର ବ୍ୟବହାର କରାଯାଏ ନାହିଁ ।^[୬] ଏହା ପାଟିରେ ଦିଆଯାଏ । ^[୩] ସର୍ବାଧିକ ପ୍ରଭାବ ପ୍ରାୟ ୬ ଘଣ୍ଟା ପରେ ହୁଏ ଏବଂ ଦୁଇ ଦିନ ପର୍ଯ୍ୟନ୍ତ ରହିପାରେ । ^[୩]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ନିଦ୍ରା, ଅସ୍ଥିରତା, ଦ୍ୱନ୍ଦ୍ୱ, ଶୁଖିଲା ପାଟି ଏବଂ ଅସ୍ପଷ୍ଟ ଦୃଷ୍ଟିଶକ୍ତି ହୋଇପାରେ ।| ^[୫] ଅନ୍ୟାନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ୟୁରିନାରି ରିଟେନସନ ଏବଂ ବାତ ହୋଇପାରେ | ^[୩] ଏହା ଏକ ପ୍ରଥମ ଶ୍ରେଣୀର ଆଣ୍ଟିହିଷ୍ଟାମିନ । ^[୩]

ବ୍ରୋମଫେନିରାମିନ ୧୯୪୮ରେ ପ୍ୟାଟେଣ୍ଟ୍ ହୋଇଥିଲା ଏବଂ ୧୯୫୫ରେ ଡାକ୍ତରୀ ବ୍ୟବହାରରେ ଆସିଥିଲା ।^[୭] ଏହା ବାରମ୍ବାର ଅନ୍ୟ ଔଷଧ ଯେପରିକି ଡେକ୍ସଟ୍ରୋମେଥୋରଫାନ୍, ଗୁଏଫେନେସିନ କିମ୍ବା ସୁଡୋଏଫିଡ୍ରିନ ସହିତ ମିଶେଇ ବିକ୍ରି ହୁଏ । ^[୫] ଏହି ମିଶ୍ରଣଗୁଡ଼ିକ ଜେନେରିକ୍ ଔଷଧ ଭାବରେ ଉପଲବ୍ଧ ଏବଂ ଅପେକ୍ଷାକୃତ ଶସ୍ତା ଅଟେ । ^[୮] ^[୯]

ଆଧାର

↑ "Brompheniramine Uses, Side Effects & Warnings". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 January 2021. Retrieved 25 March 2021.
↑ Simons FE, Frith EM, Simons KJ (December 1982). "The pharmacokinetics and antihistaminic effects of brompheniramine". The Journal of Allergy and Clinical Immunology. 70 (6): 458–64. doi:10.1016/0091-6749(82)90009-4. PMID 6128358.
↑ ^୩.୦ ^୩.୧ ^୩.୨ ^୩.୩ ^୩.୪ "Brompheniramine Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 21 January 2021. Retrieved 17 July 2021.
↑ "Brompheniramine Uses, Side Effects & Warnings". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 January 2021. Retrieved 25 March 2021.
↑ ^୫.୦ ^୫.୧ ^୫.୨ "Brompheniramine Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 21 January 2021. Retrieved 17 July 2021.
↑ BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 312. ISBN 978-0-85711-369-6.{{cite book}}: CS1 maint: date format (link)
↑ Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 546. ISBN 9783527607495. Archived from the original on 2021-05-12. Retrieved 2020-12-15.
↑ "Brompheniramine / Dextromethorphan / Pseudoephedrine Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 17 May 2020. Retrieved 17 July 2021.
↑ "Compare Dimetapp Prices". GoodRx (in ଆମେରିକୀୟ ଇଂରାଜୀ). Archived from the original on 3 November 2016. Retrieved 25 March 2021.

[MTM2021-1] "Brompheniramine Uses, Side Effects & Warnings". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 January 2021. Retrieved 25 March 2021.

[pmid6128358-2] Simons FE, Frith EM, Simons KJ (December 1982). "The pharmacokinetics and antihistaminic effects of brompheniramine". The Journal of Allergy and Clinical Immunology. 70 (6): 458–64. doi:10.1016/0091-6749(82)90009-4. PMID 6128358.

[autogen1-3] ୩.୦ ^୩.୧ ^୩.୨ ^୩.୩ ^୩.୪ "Brompheniramine Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 21 January 2021. Retrieved 17 July 2021.

[autogen3-4] "Brompheniramine Uses, Side Effects & Warnings". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 28 January 2021. Retrieved 25 March 2021.

[AHFS2021-5] ୫.୦ ^୫.୧ ^୫.୨ "Brompheniramine Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 21 January 2021. Retrieved 17 July 2021.

[BNF80-6] BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 312. ISBN 978-0-85711-369-6.{{cite book}}: CS1 maint: date format (link)

[Fis2006-7] Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 546. ISBN 9783527607495. Archived from the original on 2021-05-12. Retrieved 2020-12-15.

[8] "Brompheniramine / Dextromethorphan / Pseudoephedrine Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 17 May 2020. Retrieved 17 July 2021.

[DimeGX2021-9] "Compare Dimetapp Prices". GoodRx (in ଆମେରିକୀୟ ଇଂରାଜୀ). Archived from the original on 3 November 2016. Retrieved 25 March 2021.

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