ଏଷ୍ଟ୍ରୋପିପେଟ

ଏଷ୍ଟ୍ରୋପିପେଟ
Clinical data
Trade names	Harmogen, Improvera, Ogen, Ortho-Est, Sulestrex, others
Synonyms	Piperazine estrone sulfate; Estrone sulfate piperazine salt; Pipestrone
AHFS/Drugs.com	monograph
Routes of; administration	By mouth
Identifiers
	IUPAC name [(8R,9S,13S,14S)-13-Methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate; piperazine;
ECHA InfoCard	100.027.906
Chemical and physical data
Formula	C22H32N2O5S
Molar mass	୪୩୬.୫୭ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=S(=O)(O)Oc1cc4c(cc1)[C@@H]3[C@H]([C@@H]2CCC(=O)[C@@]2(C)CC3)CC4.N1CCNCC1;
	InChI InChI=1S/C18H22O5S.C4H10N2/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;1-2-6-4-3-5-1/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);5-6H,1-4H2/t14-,15-,16+,18+;/m1./s1 ; Key:HZEQBCVBILBTEP-ZFINNJDLSA-N ;
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ଏଷ୍ଟ୍ରୋପିପେଟ (ଇଂରାଜୀ ଭାଷାରେ Estropipate), ଅନ୍ୟମାନଙ୍କ ମଧ୍ୟରେ ଓଗେନ ବ୍ରାଣ୍ଡ ଏହାର ଏକ ବିକ୍ରୟ ନାମ, ହେଉଛି ଏକ ଔଷଧ ଯାହା ଋତୁବନ୍ଦ ଏବଂ ଓଭାରି ବିଫଳତାର ଲକ୍ଷଣକୁ ଚିକିତ୍ସା କରିବା ପାଇଁ ବ୍ୟବହୃତ ।^[୧] ଋତୁବନ୍ଦ ପରବର୍ତ୍ତୀ ଓଷ୍ଟିଓପୋରୋସିସ ରୋକିବା ପାଇଁ ମଧ୍ୟ ଏହା ପୂର୍ବରୁ ବ୍ୟବହୃତ ହୋଇଥିଲା ।^[୧] ଏହା ପାଟିରେ ଦିଆଯାଏ । ^[୧]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ମୁଣ୍ଡବିନ୍ଧା, ସ୍ତନ ଯନ୍ତ୍ରଣା, ଅନିୟମିତ ଯୋନୀପଥ ରକ୍ତସ୍ରାବ, ପେଟ କଷ୍ଟ ଏବଂ ଅଇ ହୋଇପାରେ ।^[୧] ଅନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଉଚ୍ଚ ରକ୍ତଚାପ, ଯକୃତ ସମସ୍ୟା, ଉଚ୍ଚ ରକ୍ତ ଶର୍କରା ସ୍ତର, ଫୁଲା, କେଶ ଝଡ଼ିବା ଏବଂ ଯୋନୀପଥ ଖମୀର ସଂକ୍ରମଣ ହୋଇପାରେ ।^[୧] କ୍ୱଚିତ୍ ରକ୍ତ ଜମାଟ ବାନ୍ଧିବା କିମ୍ବା ପିତ୍ତାଶୟ ରୋଗ ହୋଇପାରେ ।^[୧] ଏହା ଏକ ଇଷ୍ଟ୍ରୋଜେନ୍, ବିଶେଷ ଭାବରେ ଇଷ୍ଟ୍ରନ୍ ସଲଫେଟ୍ ଲବଣ ଏବଂ ପିପେରାଜିନ ଯାହା ଶରୀରରେ ଏଷ୍ଟ୍ରୋନ୍ ଏବଂ ଏଷ୍ଟ୍ରାଡିଓଲରେ ପରିଣତ ହୁଏ ।^[୨] ^[୩]

୧୯୫୦ ମସିହାରେ ପ୍ରଥମେ ଆମେରିକାରେ ଏଷ୍ଟ୍ରୋପିପେଟ ବ୍ୟବସାୟିକ ଭାବରେ ତିଆରି କରାଯାଇଥିଲା ।^[୪] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ୦.୭୫ ମିଗ୍ରା ବିଶିଷ୍ଟ ୧୦୦ ବଟିକାର ମୂଲ୍ୟ ପ୍ରାୟ ୫୦ ଡଲାର ଥିଲା ।^[୫] ୨୦୨୧ ସୁଦ୍ଧା ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହାର ଉତ୍ପାଦନ ବନ୍ଦ ହୋଇଯାଇଛି ।^[୬] ^[୭]

ଆଧାର

↑ ^୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ ^୧.୫ ^୧.୬ "DailyMed - ESTROPIPATE tablet". dailymed.nlm.nih.gov. Archived from the original on 11 January 2022. Retrieved 17 December 2021.
↑ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 900–. ISBN 978-1-4757-2085-3. Archived from the original on 27 June 2021. Retrieved 19 October 2020.
↑ Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 114–. ISBN 978-94-011-4439-1.
↑ Report on Carcinogens: Carcinogen Profiles (in ଇଂରାଜୀ). Department of Health and Human Services, Public Health Service, National Toxicology Program. 2000. p. RA1-PA26. Archived from the original on 2022-01-11. Retrieved 2021-12-17.
↑ "Estropipate Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Retrieved 17 December 2021.
↑ "Estropipate Prices and Estropipate Coupons - GoodRx". GoodRx. Retrieved 17 December 2021.
↑ "Drugs@FDA: FDA-Approved Drugs". www.accessdata.fda.gov. Archived from the original on 22 March 2021. Retrieved 19 December 2021.

[PI2021-1] ୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ ^୧.୪ ^୧.୫ ^୧.୬ "DailyMed - ESTROPIPATE tablet". dailymed.nlm.nih.gov. Archived from the original on 11 January 2022. Retrieved 17 December 2021.

[Elks2014-2] Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 900–. ISBN 978-1-4757-2085-3. Archived from the original on 27 June 2021. Retrieved 19 October 2020.

[MortonHall2012-3] Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 114–. ISBN 978-94-011-4439-1.

[4] Report on Carcinogens: Carcinogen Profiles (in ଇଂରାଜୀ). Department of Health and Human Services, Public Health Service, National Toxicology Program. 2000. p. RA1-PA26. Archived from the original on 2022-01-11. Retrieved 2021-12-17.

[5] "Estropipate Prices, Coupons & Patient Assistance Programs". Drugs.com (in ଇଂରାଜୀ). Retrieved 17 December 2021.

[6] "Estropipate Prices and Estropipate Coupons - GoodRx". GoodRx. Retrieved 17 December 2021.

[7] "Drugs@FDA: FDA-Approved Drugs". www.accessdata.fda.gov. Archived from the original on 22 March 2021. Retrieved 19 December 2021.

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