ସେଫପ୍ରୋଜିଲ

ସେଫପ୍ରୋଜିଲ
Clinical data
Trade names	Cefzil, Cefproz, others
Synonyms	Cephprozil, cefproxil
AHFS/Drugs.com	monograph
MedlinePlus	a698022
data	US FDA: Cefprozil;
Pregnancy; category	US: B (No risk in non-human studies) ; ;
Routes of; administration	By mouth
Legal status
Legal status	US: ℞-only ;
Pharmacokinetic data
Bioavailability	95%
Protein binding	36%
Elimination half-life	1.3 hours
Identifiers
	IUPAC name 7-[2-amino-2-(4-hydroxyphenyl)-acetyl]amino-8-oxo-3-prop-1-enyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;
Chemical and physical data
Formula	C18H19N3O5S
Molar mass	୩୮୯.୪୩ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C2N1/C(=C(/C=C/C)CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccc(O)cc3)N)C(=O)O.O;
	InChI InChI=1S/C18H19N3O5S.H2O/c1-2-3-10-8-27-17-13(16(24)21(17)14(10)18(25)26)20-15(23)12(19)9-4-6-11(22)7-5-9;/h2-7,12-13,17,22H,8,19H2,1H3,(H,20,23)(H,25,26);1H2/b3-2-;/t12-,13-,17-;/m1./s1 ; Key:ALYUMNAHLSSTOU-HERYOFLYSA-N ;
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ସେଫପ୍ରୋଜିଲ ହେଉଛି ଏକ ଆଣ୍ଟିବାୟୋଟିକ୍ ଯାହା ମଧ୍ୟକର୍ଣ୍ଣ ସଂକ୍ରମଣ, ଚର୍ମ ସଂକ୍ରମଣ, ଷ୍ଟ୍ରେପ୍ ଗଳା ଏବଂ ନିମୋନିଆର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ । ^[୧] ସାଇନୁସାଇଟିସ୍ ପାଇଁ ଏହା ଆଉ ସୁପାରିଶ କରାଯାଏ ନାହିଁ । ^[୧] ଏହା ପାଟିରେ ଦିଆଯାଏ । ^[୧]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ତରଳ ଝାଡ଼ା, ଅଇ, ଯକୃତ ସମସ୍ୟା, ଦାଗ, ମୁଣ୍ଡ ବୁଲାଇବା ଏବଂ ଯୋନୀପଥ ଇଷ୍ଟ ସଂକ୍ରମଣ ହୋଇପାରେ । ^[୨] ଅନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଆଲର୍ଜି ପ୍ରତିକ୍ରିୟା ଏବଂ କ୍ଲୋଷ୍ଟ୍ରିଡିଏଡେସ୍ ଡିଫିସିଲ୍ ସଂକ୍ରମଣ ହୋଇପାରେ । ^[୨] ଗର୍ଭାବସ୍ଥାରେ କ୍ଷତିର କୌଣସି ପ୍ରମାଣ ନଥିବାବେଳେ, ଏପରି ବ୍ୟବହାର ଭଲ ଅଧ୍ୟୟନ କରାଯାଇ ନାହିଁ । ^[୩] ଏହି ଔଷଧ ଦ୍ୱିତୀୟ ପିଢ଼ୀରସେଫାଲୋସ୍ପୋରିନ୍ ପରିବାରରେ ଅଛି । ^[୪]

୧୯୮୩ ମସିହାରେ ସେଫପ୍ରୋଜିଲ୍ ପ୍ୟାଟେଣ୍ଟ୍ ହୋଇଥିଲା ଏବଂ ୧୯୯୧ରେ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ ଅନୁମୋଦିତ ହୋଇଥିଲା। ^[୫] ^[୧] ଏହା ଏକ ସାଧାରଣ ଔଷଧ ଭାବରେ ଉପଲବ୍ଧ। ^[୬] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ୫୦୦ମିଗ୍ରାର ୨୦ଟି ବଟିକାର ମୂଲ୍ୟ ୨୦୨୧ ସୁଦ୍ଧା ପ୍ରାୟ ୨୪ ଡଲାର ଅଟେ। ^[୬]

ଆଧାର ସମ୍ପାଦନା

↑ ^୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ "Cefprozil Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 8 May 2021. Retrieved 30 December 2021.
↑ ^୨.୦ ^୨.୧ "DailyMed - CEFPROZIL tablet, film coated". dailymed.nlm.nih.gov. Archived from the original on 28 December 2021. Retrieved 30 December 2021.
↑ "Cefprozil (Cefzil) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 23 January 2021. Retrieved 30 December 2021.
↑ Beauduy, Camille E.; Winston, Lisa G. (2020). "43. Beta-lactam and other cell wall - & membrane - active antibiotics". In Katzung, Bertram G.; Trevor, Anthony J. (eds.). Basic and Clinical Pharmacology (in ଇଂରାଜୀ) (15th ed.). New York: McGraw-Hill. p. 832. ISBN 978-1-260-45231-0. Archived from the original on 2021-10-10. Retrieved 2021-11-30.
↑ Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 496. ISBN 9783527607495. Archived from the original on 2021-06-19. Retrieved 2021-05-26. {{cite book}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
↑ ^୬.୦ ^୬.୧ "Cefprozil". Archived from the original on 29 October 2016. Retrieved 30 December 2021.

[AHFS2021-1] ୧.୦ ^୧.୧ ^୧.୨ ^୧.୩ "Cefprozil Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 8 May 2021. Retrieved 30 December 2021.

[PI2021-2] ୨.୦ ^୨.୧ "DailyMed - CEFPROZIL tablet, film coated". dailymed.nlm.nih.gov. Archived from the original on 28 December 2021. Retrieved 30 December 2021.

[3] "Cefprozil (Cefzil) Use During Pregnancy". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 23 January 2021. Retrieved 30 December 2021.

[Katzung2021-4] Beauduy, Camille E.; Winston, Lisa G. (2020). "43. Beta-lactam and other cell wall - & membrane - active antibiotics". In Katzung, Bertram G.; Trevor, Anthony J. (eds.). Basic and Clinical Pharmacology (in ଇଂରାଜୀ) (15th ed.). New York: McGraw-Hill. p. 832. ISBN 978-1-260-45231-0. Archived from the original on 2021-10-10. Retrieved 2021-11-30.

[Fis2006-5] Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery (in ଇଂରାଜୀ). John Wiley & Sons. p. 496. ISBN 9783527607495. Archived from the original on 2021-06-19. Retrieved 2021-05-26. {{cite book}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)

[GX2021-6] ୬.୦ ^୬.୧ "Cefprozil". Archived from the original on 29 October 2016. Retrieved 30 December 2021.

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