"ଟେଷ୍ଟୋଷ୍ଟେରନ(ଔଷଧ)" ପୃଷ୍ଠାର ସଂସ୍କରଣ‌ଗୁଡ଼ିକ ମଧ୍ୟରେ ତଫାତ

Testosterone
Clinical data
Pronunciation	/tɛˈstɒstəroʊn/ TEH-STOS-TƏ-rohn
Trade names	AndroGel, Testim, TestoGel, others
Synonyms	Androst-4-en-17β-ol-3-one
AHFS/Drugs.com	monograph
MedlinePlus	a619028
data	EU EMA: yes; US DailyMed: Testosterone;
Pregnancy; category	AU: D ; US: X (Contraindicated) ; Contraindicated due to teratogenic effects;
Routes of; administration	Oral, buccal, sublingual, intranasal, transdermal (gel, cream, patch, solution), vaginal (cream, gel, suppository), rectal (suppository), intramuscular or subcutaneous injection (oil solution, aqueous suspension), subcutaneous implant (pellet)
Legal status
Legal status	CA: Schedule IV ; UK: Class C ; US: Schedule III ; ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	Oral: very low (due to extensive first pass metabolism)
Protein binding	97.0–99.5% (to SHBG and albumin)
Metabolism	Liver (mainly reduction and conjugation)
Elimination half-life	2–4 hours[ଆଧାର ଲୋଡ଼ା]
Excretion	Urine (90%), feces (6%)
Identifiers
	IUPAC name (8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one;
Chemical and physical data
Formula	C19H28O2
Molar mass	288.431
3D model (JSmol)	Interactive image;
Specific rotation	+110.2°
Melting point	155 °C (311 °F)
	SMILES O=C4\C=C2/[C@]([C@H]1CC[C@@]3([C@@H](O)CC[C@H]3[C@@H]1CC2)C)(C)CC4;
	InChI InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1 ; Key:MUMGGOZAMZWBJJ-DYKIIFRCSA-N ;
(verify)

ନୂଆ ବଦଳ →

Content deleted Content added

ଭିଜୁଆଲWikitext

Inline

୦୯:୩୬, ୧୩ ଜୁଲାଇ ୨୦୨୧ ଅନୁସାରେ କରାଯାଇଥିବା ବଦଳ

ଟେଷ୍ଟୋଷ୍ଟେରନ (ଟି) ହେଉଛି ଏକ ଔଷଧ ଯାହା ପ୍ରାକୃତିକ ଭାବରେ ଷ୍ଟେରଏଡ୍ ହରମୋନ୍ ଭାରେ ଥାଏ | ପୁରୁଷ ହାଇପୋଗୋନାଡିଜ୍ମ, ଲେଙ୍ଗ ଡିସଫୋରିଆ ଓ କେତେକ ପ୍ରକାରର ସ୍ତନ କର୍କଟ ରୋଗର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ | ^[୪] ଏହା ଡୋପିଂ (doping) ଆକାରରେ ଆଥଲେଟିକ ଦକ୍ଷତା ବୃଦ୍ଧି ପାଇଁ ମଧ୍ୟ ବ୍ୟବହୃତ ହୋଇପାରେ | ^[୪] ବାର୍ଦ୍ଧକ୍ୟରେ ଏହି ସ୍ତର କମ ହେଉଥିବାରୁ ଟେଷ୍ଟୋଷ୍ଟେରନର ବ୍ୟବହାର ଲାଭଦାୟକ କି କ୍ଷତିକାରକ ତାହା ଅସ୍ପଷ୍ଟ। ଟେଷ୍ଟୋସ୍ଟେରନ ବ୍ୟବହାର ଜେଲ, ପ୍ୟାଚ ଆକାରରେ ଚର୍ମରେ ଲଗାଯାଏ, ମାଂସପେଶୀରେ ଇଞ୍ଜେକସନ ଆକାରରେ ଓ ପାଟିରେ ବଟିକା ଆକାରରେ ଦିଆଯାଏ । ^[୪]

↑ ^୧.୦ ^୧.୧ "Testosterone Use During Pregnancy". Drugs.com. 20 August 2019. Retrieved 8 January 2020.
↑ Testosterone. Oxford Dictionaries.
↑ Melmed, Shlomo; Polonsky, Kenneth S.; Larsen, P. Reed; Kronenberg, Henry M. (11 November 2015). Williams Textbook of Endocrinology. Elsevier Health Sciences. pp. 709, 711, 765. ISBN 978-0-323-34157-8. {{cite book}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
↑ ^୪.୦ ^୪.୧ ^୪.୨ "Testosterone". Drugs.com. American Society of Health-System Pharmacists. ଡିସେମ୍ବର 4, 2015. Archived from the original on ଅଗଷ୍ଟ 20, 2016. Retrieved ସେପ୍ଟେମ୍ବର 3, 2016.

[Drugs.com_pregnancy-1] ୧.୦ ^୧.୧ "Testosterone Use During Pregnancy". Drugs.com. 20 August 2019. Retrieved 8 January 2020.

[2] Testosterone. Oxford Dictionaries.

[MelmedPolonsky2015-3] Melmed, Shlomo; Polonsky, Kenneth S.; Larsen, P. Reed; Kronenberg, Henry M. (11 November 2015). Williams Textbook of Endocrinology. Elsevier Health Sciences. pp. 709, 711, 765. ISBN 978-0-323-34157-8. {{cite book}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)

[AHFS2016-4] ୪.୦ ^୪.୧ ^୪.୨ "Testosterone". Drugs.com. American Society of Health-System Pharmacists. ଡିସେମ୍ବର 4, 2015. Archived from the original on ଅଗଷ୍ଟ 20, 2016. Retrieved ସେପ୍ଟେମ୍ବର 3, 2016.

[୨]

[୧]

[୩]

[୪]

Clinical data


Pronunciation	/tɛˈstɒstəroʊn/ TEH-STOS-TƏ-rohn^[୨]
Trade names	AndroGel, Testim, TestoGel, others
Synonyms	Androst-4-en-17β-ol-3-one
AHFS/Drugs.com	monograph
MedlinePlus	a619028
data	EU EMA: yes US DailyMed: Testosterone
Pregnancy category	AU: D ^[୧] US: X (Contraindicated) ^[୧] Contraindicated due to teratogenic effects
Routes of administration	Oral, buccal, sublingual, intranasal, transdermal (gel, cream, patch, solution), vaginal (cream, gel, suppository), rectal (suppository), intramuscular or subcutaneous injection (oil solution, aqueous suspension), subcutaneous implant (pellet)
Legal status
Legal status	CA: Schedule IV UK: Class C US: Schedule III ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	Oral: very low (due to extensive first pass metabolism)
Protein binding	97.0–99.5% (to SHBG and albumin)^[୩]
Metabolism	Liver (mainly reduction and conjugation)
Elimination half-life	2–4 hours^{[ଆଧାର ଲୋଡ଼ା]}
Excretion	Urine (90%), feces (6%)
Identifiers
IUPAC name (8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Chemical and physical data
Formula	C₁₉H₂₈O₂
Molar mass	288.431
3D model (JSmol)	Interactive image
Specific rotation	+110.2°
Melting point	155 °C (311 °F)
SMILES O=C4\C=C2/[C@]([C@H]1CC[C@@]3([C@@H](O)CC[C@H]3[C@@H]1CC2)C)(C)CC4
InChI InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1^Y Key:MUMGGOZAMZWBJJ-DYKIIFRCSA-N^Y
(verify)