Largeଅତ୍ୟଧିକ amountsସାଲାଇନ mayଦେଲେ result[[ତରଳ inପଦାର୍ଥ ଓଭରଲୋଡ]] ([[:en:fluid overload|fluid overload]]), [[ଇଡିମା]] ([[:en:edema|swelling]]), [[ହାଇପରକ୍ଲୋରେମିକ ଏସିଡୋସିସ]] ([[:en:hyperchloremic acidosis|acidosis]],) andଓ [[ଅଧିକ ରକ୍ତ ସୋଡ଼ିଅମ]] ([[:en:high blood sodium|high blood sodium]].) ହୋଇପାରେ । <ref name=BNF69>{{cite book|title=British national formulary : BNF 69|date=2015|publisher=British Medical Association|isbn=9780857111562|page=683, 770|edition=69}}</ref><ref name=Pro2017/> Inଦୀର୍ଘକାଳୀନ those[[ଅଳ୍ପ withରକ୍ତ long standingସୋଡ଼ିଅମ]] ([[:en:low blood sodium|low blood sodium]]) excessiveଥିବା useରୋଗୀଙ୍କୁ mayଅଧିକ resultସାଲାଇନ inଦେଲେ [[ଅସମୋଟିକ ଡିମାୟେଲିନେସନ ସିଣ୍ଡ୍ରୋମ]] ([[:en:osmotic demyelination syndrome|osmotic demyelination syndrome]].) ହୋଇପାରେ ।<ref name=BNF69/> Salineଏହା is[[ଭଲ୍ୟୁମ in theଏକ୍ସପାଣ୍ଡର]] ([[:en:Volume_expander#Crystalloids|crystalloid]]) familyଶ୍ରେଣୀର ofଏକ medications.ଔଷଧ ।<ref>{{cite book|last1=Marini|first1=John J.|last2=Wheeler|first2=Arthur P.|title=Critical Care Medicine: The Essentials|date=2010|publisher=Lippincott Williams & Wilkins|isbn=9780781798396|page=54|url=https://books.google.ca/books?id=jmxl0ERFvYgC&pg=PA54|language=en}}</ref> {{^| It is most commonly used as a [[Sterilization (microbiology)|sterile]] 9 g of salt per litre (0.9%) solution, known as normal saline.<ref name=Pro2017/> Higher and lower concentrations may also occasionally be used.<ref>{{cite web|title=Hypertonic Saline - FDA prescribing information, side effects and uses|url=https://www.drugs.com/pro/hypertonic-saline.html|website=www.drugs.com|accessdate=14 January 2017}}</ref><ref>{{cite book|last1=Pestana|first1=Carlos|title=Fluids and Electrolytes in the Surgical Patient|date=2000|publisher=Lippincott Williams & Wilkins|isbn=9780781724258|page=11|url=https://books.google.ca/books?id=CfCuIUwv3pEC&pg=PA11|language=en}}</ref>
