ଇଣ୍ଡାକାଟେରୋଲ

ଇଣ୍ଡାକାଟେରୋଲ
Clinical data
Trade names	Arcapta, Onbrez, others
Synonyms	Indacaterol maleate
AHFS/Drugs.com	monograph
data	EU EMA: yes; US DailyMed: Indacaterol;
Pregnancy; category	AU: B3 ; ;
Routes of; administration	Inhalation
Legal status
Legal status	AU: S4 (Prescription only) ; UK: POM (Prescription only) ; US: ℞-only ; EU: Rx-only ;
Identifiers
	IUPAC name 5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxyquinolin-2(1H)-one;
ECHA InfoCard	100.218.577
Chemical and physical data
Formula	C24H28N2O3
Molar mass	୩୯୨.୫0 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C4/C=C\c1c(c(O)ccc1[C@@H](O)CNC3Cc2cc(c(cc2C3)CC)CC)N4;
	InChI InChI=1S/C24H28N2O3/c1-3-14-9-16-11-18(12-17(16)10-15(14)4-2)25-13-22(28)19-5-7-21(27)24-20(19)6-8-23(29)26-24/h5-10,18,22,25,27-28H,3-4,11-13H2,1-2H3,(H,26,29)/t22-/m0/s1 ; Key:QZZUEBNBZAPZLX-QFIPXVFZSA-N ;
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ଇଣ୍ଡାକାଟେରୋଲ (ଇଂରାଜୀ ଭାଷାରେ Indacaterol), ଅନ୍ୟମାନଙ୍କ ମଧ୍ୟରେ ଅନବ୍ରେଜ ଏକ ବେପାର ନାମ, ହେଉଛି ଏକ ଔଷଧ ଯାହା କ୍ରନିକ ଅବଷ୍ଟ୍ରକ୍ଟିଭ ଫୁସଫୁସ ରୋଗ (COPD) ର ଚିକିତ୍ସା ପାଇଁ ବ୍ୟବହୃତ ହୁଏ ।^[୫] ଦିନକୁ ଥରେ ଶୁଖିଲା ପାଉଡର ଆଘ୍ରାଣ ସାହାଯ୍ୟରେ ଏହା ଦିଆଯାଏ ।^[୫]

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ଉର୍ଦ୍ଧ୍ୱ ଶ୍ୱାସନଳୀ ସଂକ୍ରମଣ, ଛାତି ଯନ୍ତ୍ରଣା ଏବଂ କାଶ ହୋଇପାରେ ।^[୬] ଆଜ୍‌ମା ରୋଗୀଙ୍କୁ ଦେଲେ ଏହା ଯୋଗୁ ମୃତ୍ୟୁ ଆଶଙ୍କା ବଢ଼ିଯାଇପାରେ। ^[୫] ଏହା ଏକ ଦୀର୍ଘ କାର୍ଯ୍ୟକାରୀ ବିଟା-ଆଡ୍ରେନୋସେପ୍ଟର ଆଗୋନିଷ୍ଟ (LABA) ଔଷଧ ।^[୫]

୨୦୦୯ ମସିହାରେ ୟୁରୋପରେ ଏବଂ ୨୦୧୧ରେ ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଚିକିତ୍ସା କ୍ଷେତ୍ରରେ ବ୍ୟବହାର ପାଇଁ ଇଣ୍ଡାକାଟେରୋଲକୁ ଅନୁମୋଦନ କରାଯାଇଥିଲା ।^[୬] ^[୫] ଯୁକ୍ତରାଜ୍ୟରେ ୨୦୨୧ ସୁଦ୍ଧା ଏହା ପିଛା ମାସକୁ ପ୍ରାୟ ୩୨ ପାଉଣ୍ଡ ଖର୍ଚ୍ଚ ହୁଏ ।^[୭] ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହି ରାଶିର ମୂଲ୍ୟ ପ୍ରାୟ ୨୬୦ ଡଲାର ଅଟେ ।^[୮]

ଆଧାର ସମ୍ପାଦନା

↑ "Onbrez Breezhaler EPAR". European Medicines Agency (EMA). Archived from the original on 28 January 2021. Retrieved 20 January 2021.
↑ "Oslif Breezhaler EPAR". European Medicines Agency (EMA). Archived from the original on 28 January 2021. Retrieved 20 January 2021.
↑ "Hirobriz Breezhaler EPAR". European Medicines Agency (EMA). Archived from the original on 28 January 2021. Retrieved 20 January 2021.
↑ "Arcapta Neohaler (indacaterol) inhalation powder Initial U.S. Approval: 2011". DailyMed. 1 April 2020. Archived from the original on 15 June 2021. Retrieved 14 June 2021.
↑ ^୫.୦ ^୫.୧ ^୫.୨ ^୫.୩ ^୫.୪ "Indacaterol Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 22 January 2021. Retrieved 26 November 2021.
↑ ^୬.୦ ^୬.୧ "Onbrez Breezhaler". Archived from the original on 28 January 2021. Retrieved 26 November 2021.
↑ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 267. ISBN 978-0857114105.
↑ "Indacaterol Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 26 November 2021.

[1] "Onbrez Breezhaler EPAR". European Medicines Agency (EMA). Archived from the original on 28 January 2021. Retrieved 20 January 2021.

[2] "Oslif Breezhaler EPAR". European Medicines Agency (EMA). Archived from the original on 28 January 2021. Retrieved 20 January 2021.

[3] "Hirobriz Breezhaler EPAR". European Medicines Agency (EMA). Archived from the original on 28 January 2021. Retrieved 20 January 2021.

[4] "Arcapta Neohaler (indacaterol) inhalation powder Initial U.S. Approval: 2011". DailyMed. 1 April 2020. Archived from the original on 15 June 2021. Retrieved 14 June 2021.

[AHFS2021-5] ୫.୦ ^୫.୧ ^୫.୨ ^୫.୩ ^୫.୪ "Indacaterol Monograph for Professionals". Drugs.com (in ଇଂରାଜୀ). Archived from the original on 22 January 2021. Retrieved 26 November 2021.

[EPAR2021-6] ୬.୦ ^୬.୧ "Onbrez Breezhaler". Archived from the original on 28 January 2021. Retrieved 26 November 2021.

[BNF81-7] BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 267. ISBN 978-0857114105.

[8] "Indacaterol Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 26 November 2021.

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